Barone, P.W., Keumurian, F.J., Neufeld, C., Koenigsberg, A., Kiss, R., Leung, J.C., Wiebe, M., Ait-Belkacem, R., Azimpour – Tabrizi, C., Barbirato, C., Beurdeley, P., Brussel, A., Cassart, J.P., Cote, C., Deneyer, N., Dheenadhayalan, V., Diaz, L., Geiselhoeringer, A., Gilleece, M.M., Goldmann, J., Hickman, D., Holden, A., Keiner, B., Kopp, M., Kreil, T.R., Lambert, C., Logvinoff, C., Michaels, B., Modrof, J., Mullan, B., Mullberg, J., Murphy, M., O’Donnell, S., Peña, J., Ruffing, M., Ruppach, H., Salehi, N., Shaid, S., Silva, L., Snyder, R., Spedito-Jovial, M., Vandeputte, O., Westrek, B., Yang, B., Yang, P., Springs, S.L.
Historical evaluation of the in vivo adventitious virus test and its potential for replacement with next generation sequencing (NGS)
Biologicals, January 6, 2023
Swofford, C.A., Nordeen, S.A., Chen, L., Desai, M.M., Chen, J., Springs, S.L., Schwartz, T.U., Sinskey, A.J.,
Structure and specificity of an anti-chloramphenicol single domain antibody for detection of amphenicol residues.
Protein Science, Volume 31, Issue 11, November 2022
Koenigsberg, A.L., Fowler, V., Domike, R., Brussel, A., Barone, P.W., Keumurian, F.J., Leung, J.C., Wiebe, M.E., Brewer, M.T., Chan, S., Dumey, N., Fournillier, A., Goodnight, M., Kindermann, J., Leavy, R., Lee, B., Minning, S., Murphy, M., Myers, E., Nahabedian, A., Nanda, K., Parriott, S., Raju, G.K., Scallan, C., Schoch, S., Shiminsky, J., Shum, B., Teitz, S., Westrek, B., Springs, S.L.MIT CAACB Risk Assessment Case Study: Assessing virus cross-contamination risk between two simultaneous processes in an open biomanufacturing facility.
PDA Journal of Pharmaceutical Science and Technology, October, 2022
Katsikis, G., Hwang, I.E., Wang, W., Bhat, V.S., McIntosh, N.L., Karim, O.A., Blus, B.J., Sha, S., Agache, V., Wolfrum, J.M., Springs, S.L., Sinskey, A.J., Barone, P.W., Braatz, R.D., Manalis, S.R.
Weighing the DNA content of adeno-associated virus vectors with Zeptogram precision using nanomechanical resonators.
Nano Letters, 2022, 22, 4, 1511-1517
Huang, J., Cuie, L., Natarajan, M., Barone, P.W., Wolfrum, J., Lee, Y.H., Rice, S.A., Springs, S.L.
The ratio of nicotinic acid to nicotinamide as a microbial biomarker for assessing cell therapy product sterility.
Molecular Therapy – Methods & Clinical Development, April 2022
Wu, X., Chan, C., Springs, S.L., Lee, Y.H., Lu, T.K., Yu, H.,
A warm-start digital CRISPR/Cas-based method for the quantitative detection of nucleic acids.
Analytica Chimica Acta, Volume 1196, March 2022
Wu, X., Tay, J.K., Goh, C.K., Chan, C., Lee, Y.H.
, Springs, S.L., Wang, D.Y., Loh, K.S., Lu, T.K., Yu, H.
A Rapid DIgital Crispr Approach (RADICA) for the detection and absolute quantification of nucleic acids.
Frontiers in Biological Detection: From Nanosensors to Systems XIV, Volume PC11979, March 2022
Hong, M.S., Lu, A.E., Maloney, A.J., Ou, R.W., Wolfrum, J.M., Springs, S.L., Sinskey, A.J., Braatz, R.D.
Applying PAT to the continuous digital biomanufacturing of monoclonal antibodies.
Pharma Focus Asia, Volume 44, 42-46, 2022
Chen, L.,
Guttieres, D., Koenigsburg, A., Barone, P.W.,
Sinskey, A.J., Springs, S.L.,
Large-scale cultured meat production: Trends, challenges and promising biomanufacturing technologies.
Biomaterials, Volume 280, January 2022
Wu, X., Tay, J.K., Goh, C.K., Chan, C., Lee, Y.H., Springs, S.L., Wang, D.Y., Loh, K.S., Lu, T.K., Yu, H.
Digital CRISPR-based method for the rapid detection and absolute quantification of nucleic acids.
Biomaterials, July 2021, 120876
Nguyen, T.N.T., Sha, S., Hong, M.S., Maloney, A.J., Barone, P.W., Neufeld, C., Wolfrum, J.M., Springs, S.L., Sinskey, A.J., Braatz, R.D.
Mechanistic model for production of recombinant adeno-associated virus via triple transfection of HEK293 cells.
Molecular Therapy, Methods & Clinical Development, June 2021, Vol. 21, 642-655
Sha, S., Maloney, A.J., Katsikis, G., Nguyen, T.N.T., Neufeld, C., Wolfrum, J., Barone, P.W., Springs, S.L., Manalis, S.R., Sinskey A.J.
, Braatz, R.D.
Cellular Pathways of recombinant Adeno-Associated Virus Production for Gene Therapy.
Biotechnology Advances, Volume 49, May 2021
Su, J., Rice, J., Hoffman, J., Alvarado, S., Bailey, M., Kopp, M., Murphy, M., Kiss, R., Barone, P.W., Wiebe, M.E., Springs, S.L., Dehghani, H., Chen, D.
Revisiting mouse minute virus inactivation by high temperature short time treatment.
Biotechnology & Bioengineering, April 29, 2021
Gimpel, A.L., Katsikis, G., Sha, S., Maloney, A.J., Hong, M.S.,Nguyen, T., Wolfrum, J., Sinskey, A.J., Manalis, S.R., Barone, P.W., Braatz, R.D., Springs, S.L.,
Analytical Methods for Process and Product Characterization of Recombinant Adeno-Associated Virus-based Gene Therapies.
Molecular Therapies – Methods & Clinical Development. 2021
Jin, C., Levi, R., Liang, Q., Renegar, N., Zhou, J., Zhou, W., Springs, S.L.
Testing at the Source: Analytics-Enabled Risk-Based Sampling of Food Supply Chains in China.Management Science, 22, Jan., 2021
P.W. Barone, F.J. Keumurian, M.E. Wiebe, J. Wolfrum, J.C. Leung, A.J. Sinskey, S.L. Springs
The Impact of SARS-CoV-2 on Biomanufacturing Operations.BioPharm International, Volume 33, Issue 8, August 1, 2020
Wu, X., Chan, C., Lee, Y.H., Lu, T.K., Yu, H., Springs, S.L.
A Digital CRISPR-based Method for the Rapid Detection and Absolute Quantification of Viral Nucleic Acids.medRxiv, 2020
Barone, P.W., Keumurian, F.J., Leung, J, Springs, S.L., Domike, R., Raju, G.K., Monpoeho, S., Murray, K., Reich, S., Ruffing, M., Wiebe, M.
“Quality Risk Management in the Context of Viral Contamination”.
In Microbial Control and Identification, edited by Donna Reber, PDA, Washington, 2018
Stewart, S.R., Barone, P.W., . Bellisario, A., Cooney, C.L., Sharp, P.A., Sinskey, A.J., Natesan, S., Springs, S.L.
Leveraging Industry-Academia Collaborations in Adaptive Biomedical Innovation.
Clin. Pharm. Ther. 100 (6), 647-653. PMID: 27617845, 2016
US Chapter of the United Nations Educational, Scientific and Cultural Organization (UNESCO) 2015 Science Report: “The United States of America.” S.R. Stewart and S.L.Springs.
UNESCO Science Report 2015: Towards 2030.UNESCO Publishing. November 10, 2015.Koenigburg
